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Expansion of Human Mesenchymal Stromal Cells from Fresh Bone Marrow in a 3D Scaffold-Based System under Direct Perfusion
Mesenchymal stromal/stem cell (MSC) expansion in conventional monolayer culture on plastic dishes (2D) leads to progressive loss of functionality and thus challenges fundamental studies on the physiology of skeletal progenitors, as well as translational applications for cellular therapy and molecula...
Autores principales: | Papadimitropoulos, Adam, Piccinini, Elia, Brachat, Sophie, Braccini, Alessandra, Wendt, David, Barbero, Andrea, Jacobi, Carsten, Martin, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096512/ https://www.ncbi.nlm.nih.gov/pubmed/25020062 http://dx.doi.org/10.1371/journal.pone.0102359 |
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