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Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways

BACKGROUND: Dillenia suffruticosa root dichloromethane extract (DCM-DS) has been reported to exhibit strong cytotoxicity towards breast cancer cells. The present study was designed to investigate the cell cycle profile, mode of cell death and signalling pathways of DCM-DS-treated human caspase-3 def...

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Detalles Bibliográficos
Autores principales: Foo, Jhi Biau, Yazan, Latifah Saiful, Tor, Yin Sim, Armania, Nurdin, Ismail, Norsharina, Imam, Mustapha Umar, Yeap, Swee Keong, Cheah, Yoke Kqueen, Abdullah, Rasedee, Ismail, Maznah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096536/
https://www.ncbi.nlm.nih.gov/pubmed/24947113
http://dx.doi.org/10.1186/1472-6882-14-197