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Chronic Ingestion of H1-Antihistamines Increase Progression of Atherosclerosis in Apolipoprotein E-/- Mice
Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals. In order to elucidate how pharmacological inhi...
Autores principales: | Raveendran, Vineesh V., Smith, Donald D., Tan, Xiaoyu, Sweeney, Matthew E., Reed, Gregory A., Flynn, Colleen A., Tawfik, Ossama W., Milne, Ginger, Dileepan, Kottarappat N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096593/ https://www.ncbi.nlm.nih.gov/pubmed/25020133 http://dx.doi.org/10.1371/journal.pone.0102165 |
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