Cargando…
Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA)
BACKGROUND: It is estimated that about 275,000 inhabitants experience an out-of-hospital cardiac arrest (OHCA) every year in Europe. Survival in out-of-hospital cardiac arrest is relatively low, generally between five per cent and 10%. Being able to explore new methods to improve the relatively low...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096750/ https://www.ncbi.nlm.nih.gov/pubmed/24993861 http://dx.doi.org/10.1186/1471-227X-14-15 |
_version_ | 1782326172040822784 |
---|---|
author | Jiménez-Herrera, María F Azeli, Youcef Valero-Mora, Eva Lucas-Guarque, Isaac López-Gomariz, Alfonso Castro-Naval, Elena Axelsson, Christer |
author_facet | Jiménez-Herrera, María F Azeli, Youcef Valero-Mora, Eva Lucas-Guarque, Isaac López-Gomariz, Alfonso Castro-Naval, Elena Axelsson, Christer |
author_sort | Jiménez-Herrera, María F |
collection | PubMed |
description | BACKGROUND: It is estimated that about 275,000 inhabitants experience an out-of-hospital cardiac arrest (OHCA) every year in Europe. Survival in out-of-hospital cardiac arrest is relatively low, generally between five per cent and 10%. Being able to explore new methods to improve the relatively low survival rate is vital for people with these conditions. Passive leg raise (PLR) during cardiopulmonary resuscitation (CPR) has been found to improve cardiac preload and blood flow during chest compressions. The aim of our study is to evaluate whether early PLR during CPR also has an impact on one-month survival in sudden and unexpected out-of-hospital cardiac arrest (OHCA). METHOD/DESIGN: A prospective, randomized, controlled trial in which all patients (≥18 years) receiving out-of hospital CPR are randomized by envelope to be treated with either PLR or in the flat position. The ambulance crew use a special folding stool which allows the legs to be elevated about 20 degrees. Primary end-point: survival to one month. Secondary end-point: survival to hospital admission to one month and to one year with acceptable cerebral performance classification (CPC) 1–2. DISCUSSION: PLR is a simple and fast maneuver. We believe that the greatest benefit with PLR is when performed early in the process, during the first minutes of CPR and before the first defibrillation. To reach power this study need 3000 patients, we hope that this method article will encourage other sites to contact us and take part in our study. TRIAL REGISTRATION: ClinicalTrials.gov NCT01952197. |
format | Online Article Text |
id | pubmed-4096750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40967502014-07-16 Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) Jiménez-Herrera, María F Azeli, Youcef Valero-Mora, Eva Lucas-Guarque, Isaac López-Gomariz, Alfonso Castro-Naval, Elena Axelsson, Christer BMC Emerg Med Study Protocol BACKGROUND: It is estimated that about 275,000 inhabitants experience an out-of-hospital cardiac arrest (OHCA) every year in Europe. Survival in out-of-hospital cardiac arrest is relatively low, generally between five per cent and 10%. Being able to explore new methods to improve the relatively low survival rate is vital for people with these conditions. Passive leg raise (PLR) during cardiopulmonary resuscitation (CPR) has been found to improve cardiac preload and blood flow during chest compressions. The aim of our study is to evaluate whether early PLR during CPR also has an impact on one-month survival in sudden and unexpected out-of-hospital cardiac arrest (OHCA). METHOD/DESIGN: A prospective, randomized, controlled trial in which all patients (≥18 years) receiving out-of hospital CPR are randomized by envelope to be treated with either PLR or in the flat position. The ambulance crew use a special folding stool which allows the legs to be elevated about 20 degrees. Primary end-point: survival to one month. Secondary end-point: survival to hospital admission to one month and to one year with acceptable cerebral performance classification (CPC) 1–2. DISCUSSION: PLR is a simple and fast maneuver. We believe that the greatest benefit with PLR is when performed early in the process, during the first minutes of CPR and before the first defibrillation. To reach power this study need 3000 patients, we hope that this method article will encourage other sites to contact us and take part in our study. TRIAL REGISTRATION: ClinicalTrials.gov NCT01952197. BioMed Central 2014-07-04 /pmc/articles/PMC4096750/ /pubmed/24993861 http://dx.doi.org/10.1186/1471-227X-14-15 Text en Copyright © 2014 Herrera et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Study Protocol Jiménez-Herrera, María F Azeli, Youcef Valero-Mora, Eva Lucas-Guarque, Isaac López-Gomariz, Alfonso Castro-Naval, Elena Axelsson, Christer Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title | Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title_full | Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title_fullStr | Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title_full_unstemmed | Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title_short | Passive leg raise (PLR) during cardiopulmonary (CPR) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA) |
title_sort | passive leg raise (plr) during cardiopulmonary (cpr) – a method article on a randomised study of survival in out-of-hospital cardiac arrest (ohca) |
topic | Study Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096750/ https://www.ncbi.nlm.nih.gov/pubmed/24993861 http://dx.doi.org/10.1186/1471-227X-14-15 |
work_keys_str_mv | AT jimenezherreramariaf passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT azeliyoucef passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT valeromoraeva passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT lucasguarqueisaac passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT lopezgomarizalfonso passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT castronavalelena passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca AT axelssonchrister passivelegraiseplrduringcardiopulmonarycpramethodarticleonarandomisedstudyofsurvivalinoutofhospitalcardiacarrestohca |