Cargando…
A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique
BACKGROUND: The present study introduced a modified delta-shaped gastroduodenostomy (DSG) technique and assessed the safety, feasibility and clinical results of this procedure in patients undergoing totally laparoscopic distal gastrectomy (TLDG) for gastric cancer (GC). MATERIALS AND METHODS: A tota...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096929/ https://www.ncbi.nlm.nih.gov/pubmed/25019646 http://dx.doi.org/10.1371/journal.pone.0102736 |
_version_ | 1782326180861444096 |
---|---|
author | Huang, Changming Lin, Mi Chen, Qiyue Lin, Jianxian Zheng, Chaohui Li, Ping Xie, Jianwei Wang, Jiabin Lu, Jun |
author_facet | Huang, Changming Lin, Mi Chen, Qiyue Lin, Jianxian Zheng, Chaohui Li, Ping Xie, Jianwei Wang, Jiabin Lu, Jun |
author_sort | Huang, Changming |
collection | PubMed |
description | BACKGROUND: The present study introduced a modified delta-shaped gastroduodenostomy (DSG) technique and assessed the safety, feasibility and clinical results of this procedure in patients undergoing totally laparoscopic distal gastrectomy (TLDG) for gastric cancer (GC). MATERIALS AND METHODS: A total of 102 patients with distal GC undergoing TLDG with modified DSG between January 2013 and December 2013 were enrolled. A retrospective study was performed using a prospectively maintained comprehensive database to evaluate the results of the procedure. Univariate and multivariate analyses were performed to estimate the predictive factors for postoperative morbidity. RESULTS: The mean operation time was 150.6±30.2 min, the mean anastomosis time was 12.2±4.2 min, the mean blood loss was 48.2±33.2 ml, and the mean times to first flatus, fluid diet, soft diet and postoperative hospital stay were 3.8±1.3 days, 5.0±1.0 days, 7.4±2.1 days and 12.0±6.5 days, respectively. Two patients with minor anastomotic leakage after surgery were managed conservatively; no patient experienced any complications around the anastomosis, such as anastomotic stricture or anastomotic hemorrhage. Univariate analysis showed that age, gastric cancer with hemorrhage and cardiovascular disease combined were significant factors that affected postoperative morbidity (P<0.05). Multivariate analysis found that gastric cancer with hemorrhage was the independent risk factor for the postoperative morbidity (P = 0.042). At a median follow-up of 7 months, no patients had died or experienced recurrent or metastatic disease. CONCLUSIONS: The modified DSG was technically safe and feasible, with acceptable surgical outcomes, in patients undergoing TLDG for GC, and this procedure may be promising in these patients. |
format | Online Article Text |
id | pubmed-4096929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-40969292014-07-17 A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique Huang, Changming Lin, Mi Chen, Qiyue Lin, Jianxian Zheng, Chaohui Li, Ping Xie, Jianwei Wang, Jiabin Lu, Jun PLoS One Research Article BACKGROUND: The present study introduced a modified delta-shaped gastroduodenostomy (DSG) technique and assessed the safety, feasibility and clinical results of this procedure in patients undergoing totally laparoscopic distal gastrectomy (TLDG) for gastric cancer (GC). MATERIALS AND METHODS: A total of 102 patients with distal GC undergoing TLDG with modified DSG between January 2013 and December 2013 were enrolled. A retrospective study was performed using a prospectively maintained comprehensive database to evaluate the results of the procedure. Univariate and multivariate analyses were performed to estimate the predictive factors for postoperative morbidity. RESULTS: The mean operation time was 150.6±30.2 min, the mean anastomosis time was 12.2±4.2 min, the mean blood loss was 48.2±33.2 ml, and the mean times to first flatus, fluid diet, soft diet and postoperative hospital stay were 3.8±1.3 days, 5.0±1.0 days, 7.4±2.1 days and 12.0±6.5 days, respectively. Two patients with minor anastomotic leakage after surgery were managed conservatively; no patient experienced any complications around the anastomosis, such as anastomotic stricture or anastomotic hemorrhage. Univariate analysis showed that age, gastric cancer with hemorrhage and cardiovascular disease combined were significant factors that affected postoperative morbidity (P<0.05). Multivariate analysis found that gastric cancer with hemorrhage was the independent risk factor for the postoperative morbidity (P = 0.042). At a median follow-up of 7 months, no patients had died or experienced recurrent or metastatic disease. CONCLUSIONS: The modified DSG was technically safe and feasible, with acceptable surgical outcomes, in patients undergoing TLDG for GC, and this procedure may be promising in these patients. Public Library of Science 2014-07-14 /pmc/articles/PMC4096929/ /pubmed/25019646 http://dx.doi.org/10.1371/journal.pone.0102736 Text en © 2014 Huang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Huang, Changming Lin, Mi Chen, Qiyue Lin, Jianxian Zheng, Chaohui Li, Ping Xie, Jianwei Wang, Jiabin Lu, Jun A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title | A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title_full | A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title_fullStr | A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title_full_unstemmed | A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title_short | A Modified Delta-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Safe and Feasible Technique |
title_sort | modified delta-shaped gastroduodenostomy in totally laparoscopic distal gastrectomy for gastric cancer: a safe and feasible technique |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096929/ https://www.ncbi.nlm.nih.gov/pubmed/25019646 http://dx.doi.org/10.1371/journal.pone.0102736 |
work_keys_str_mv | AT huangchangming amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT linmi amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT chenqiyue amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT linjianxian amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT zhengchaohui amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT liping amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT xiejianwei amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT wangjiabin amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT lujun amodifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT huangchangming modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT linmi modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT chenqiyue modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT linjianxian modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT zhengchaohui modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT liping modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT xiejianwei modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT wangjiabin modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique AT lujun modifieddeltashapedgastroduodenostomyintotallylaparoscopicdistalgastrectomyforgastriccancerasafeandfeasibletechnique |