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Regulation of Cell Transformation by Rb-Controlled Redox Homeostasis

Rb is a tumor suppressor, and regulates various biological progresses, such as cell proliferation, development, metabolism and cell death. In the current study, we show that Rb knockout in 3T3 cells leads to oxidative redox state and low mitochondrial membrane potential by regulating mitochondrial a...

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Detalles Bibliográficos
Autores principales: Zhu, Zhongling, Wang, Yuanyuan, Liang, Zheng, Wang, Wenwen, Zhang, Huamei, Li, Binghui, Ying, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097070/
https://www.ncbi.nlm.nih.gov/pubmed/25019272
http://dx.doi.org/10.1371/journal.pone.0102582