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Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction
Rationale: Antibiotic treatment of patients infected with G(−) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressin...
Autores principales: | Czikora, Istvan, Sridhar, Supriya, Gorshkov, Boris, Alieva, Irina B., Kasa, Anita, Gonzales, Joyce, Potapenko, Olena, Umapathy, Nagavedi S., Pillich, Helena, Rick, Ferenc G., Block, Norman L., Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Schally, Andrew V., Lucas, Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097355/ https://www.ncbi.nlm.nih.gov/pubmed/25076911 http://dx.doi.org/10.3389/fphys.2014.00259 |
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