Identification of a Cytotoxic Form of Dimeric Interleukin-2 in Murine Tissues

Interleukin-2 (IL-2) is a multi-faceted cytokine, known for promoting proliferation, survival, and cell death depending on the cell type and state. For example, IL-2 facilitates cell death only in activated T cells when antigen and IL-2 are abundant. The availability of IL-2 clearly impacts this pro...

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Detalles Bibliográficos
Autores principales: Wrenshall, Lucile E., Clabaugh, Suzanne E., Cool, David R., Arumugam, Prakash, Grunwald, William C., Smith, Deandra R., Liu, Gino C., Miller, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097599/
https://www.ncbi.nlm.nih.gov/pubmed/25019288
http://dx.doi.org/10.1371/journal.pone.0102191

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