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Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes
INTRODUCTION: In the present study, we established a novel in vitro coculture model to evaluate the influence of osteoarthritis (OA) cartilage explants on the composition of newly produced matrix and chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells (BMSCs) and the phe...
Autores principales: | Leyh, Michaela, Seitz, Andreas, Dürselen, Lutz, Springorum, Hans-Robert, Angele, Peter, Ignatius, Anita, Grifka, Joachim, Grässel, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097830/ https://www.ncbi.nlm.nih.gov/pubmed/24916039 http://dx.doi.org/10.1186/scrt466 |
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