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Age‐related remodeling of small arteries is accompanied by increased sphingomyelinase activity and accumulation of long‐chain ceramides

The structure and function of large arteries alters with age leading to increased risk of cardiovascular disease. Age‐related large artery remodeling and arteriosclerosis is associated with increased collagen deposition, inflammation, and endothelial dysfunction. Bioactive sphingolipids are known to...

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Detalles Bibliográficos
Autores principales: Ohanian, Jacqueline, Liao, Aiyin, Forman, Simon P., Ohanian, Vasken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098743/
https://www.ncbi.nlm.nih.gov/pubmed/24872355
http://dx.doi.org/10.14814/phy2.12015