Mouse mammary tumor virus-based vector transduces non-dividing cells, enters the nucleus via a TNPO3-independent pathway and integrates in a less biased fashion than other retroviruses

BACKGROUND: Mouse mammary tumor virus (MMTV) is a complex, milk-born betaretrovirus, which preferentially infects dendritic cells (DC) in the gastrointestinal tract and then spreads to T and B lymphocytes and finally to the mammary gland. It is not clear how the prototypic betaretrovirus infects muc...

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Detalles Bibliográficos
Autores principales: Konstantoulas, Constantine James, Indik, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098793/
https://www.ncbi.nlm.nih.gov/pubmed/24779422
http://dx.doi.org/10.1186/1742-4690-11-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098793/
https://www.ncbi.nlm.nih.gov/pubmed/24779422
http://dx.doi.org/10.1186/1742-4690-11-34

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