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Novel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors

BACKGROUND: Insertional mutagenesis screens of retrovirus-induced mouse tumors have proven valuable in human cancer research and for understanding adverse effects of retroviral-based gene therapies. In previous studies, the assignment of mouse genes to individual retroviral integration sites has bee...

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Detalles Bibliográficos
Autores principales: Sokol, Martin, Wabl, Matthias, Ruiz, Irene Rius, Pedersen, Finn Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098794/
https://www.ncbi.nlm.nih.gov/pubmed/24886479
http://dx.doi.org/10.1186/1742-4690-11-36

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