Cargando…
Wnt activation promotes neuronal differentiation of Glioblastoma
One of the biggest challenges in tumour research is the possibility to reprogram cancer cells towards less aggressive phenotypes. In this study, we reprogrammed primary Glioblastoma multiforme (GBM)-derived cells towards a more differentiated and less oncogenic phenotype by activating the Wnt pathwa...
Autores principales: | Rampazzo, E, Persano, L, Pistollato, F, Moro, E, Frasson, C, Porazzi, P, Della Puppa, A, Bresolin, S, Battilana, G, Indraccolo, S, Te Kronnie, G, Argenton, F, Tiso, N, Basso, G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098797/ https://www.ncbi.nlm.nih.gov/pubmed/23429286 http://dx.doi.org/10.1038/cddis.2013.32 |
Ejemplares similares
-
Wnt activation promotes neuronal differentiation of Glioblastoma
por: Rampazzo, E, et al.
Publicado: (2013) -
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression
por: Persano, L, et al.
Publicado: (2012) -
The Three-Layer Concentric Model of Glioblastoma: Cancer Stem Cells, Microenvironmental Regulation, and Therapeutic Implications
por: Persano, Luca, et al.
Publicado: (2011) -
HIF-1α/Wnt signaling-dependent control of gene transcription regulates neuronal differentiation of glioblastoma stem cells
por: Boso, Daniele, et al.
Publicado: (2019) -
Molecular Mechanisms of HIF-1α Modulation Induced by Oxygen Tension and BMP2 in Glioblastoma Derived Cells
por: Pistollato, Francesca, et al.
Publicado: (2009)