Integrating In Silico Prediction Methods, Molecular Docking, and Molecular Dynamics Simulation to Predict the Impact of ALK Missense Mutations in Structural Perspective

Over the past decade, advancements in next generation sequencing technology have placed personalized genomic medicine upon horizon. Understanding the likelihood of disease causing mutations in complex diseases as pathogenic or neutral remains as a major task and even impossible in the structural con...

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Detalles Bibliográficos
Autores principales: Priya Doss, C. George, Chakraborty, Chiranjib, Chen, Luonan, Zhu, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098886/
https://www.ncbi.nlm.nih.gov/pubmed/25054154
http://dx.doi.org/10.1155/2014/895831

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