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Evidence-Based Nanoscopic and Molecular Framework for Excipient Functionality in Compressed Orally Disintegrating Tablets

The work investigates the adhesive/cohesive molecular and physical interactions together with nanoscopic features of commonly used orally disintegrating tablet (ODT) excipients microcrystalline cellulose (MCC) and D-mannitol. This helps to elucidate the underlying physico-chemical and mechanical mec...

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Detalles Bibliográficos
Autores principales: Al-khattawi, Ali, Alyami, Hamad, Townsend, Bill, Ma, Xianghong, Mohammed, Afzal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098910/
https://www.ncbi.nlm.nih.gov/pubmed/25025427
http://dx.doi.org/10.1371/journal.pone.0101369