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Early Activation of STAT3 Regulates Reactive Astrogliosis Induced by Diverse Forms of Neurotoxicity
Astrogliosis, a cellular response characterized by astrocytic hypertrophy and accumulation of GFAP, is a hallmark of all types of central nervous system (CNS) injuries. Potential signaling mechanisms driving the conversion of astrocytes into “reactive” phenotypes differ with respect to the injury mo...
Autores principales: | O'Callaghan, James P., Kelly, Kimberly A., VanGilder, Reyna L., Sofroniew, Michael V., Miller, Diane B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098997/ https://www.ncbi.nlm.nih.gov/pubmed/25025494 http://dx.doi.org/10.1371/journal.pone.0102003 |
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