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Wilms' Tumor Protein Induces an Epithelial-Mesenchymal Hybrid Differentiation State in Clear Cell Renal Cell Carcinoma
The Wilms' tumor transcription factor (WT1) was originally classified as a tumor suppressor, but it is now known to also be associated with cancer progression and poor prognosis in several malignancies. WT1 plays an essential role in orchestrating a developmental process known as mesenchymal-to...
Autores principales: | Sampson, Valerie B., David, Justin M., Puig, Isabel, Patil, Pratima U., de Herreros, Antonio García, Thomas, George V., Rajasekaran, Ayyappan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099076/ https://www.ncbi.nlm.nih.gov/pubmed/25025131 http://dx.doi.org/10.1371/journal.pone.0102041 |
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