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Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP)
BACKGROUND: Homologous recombination repair (HRR) pathway deficiencies have significant implications for cancer predisposition and treatment strategies. Improved quantitative methods for functionally characterizing these deficiencies are required to accurately identify patients at risk of developing...
Autores principales: | Rosen, David B, Leung, Ling Y, Louie, Brent, Cordeiro, James A, Conroy, Andrew, Shapira, Iuliana, Fields, Scott Z, Cesano, Alessandra, Hawtin, Rachael E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099151/ https://www.ncbi.nlm.nih.gov/pubmed/24965603 http://dx.doi.org/10.1186/1479-5876-12-184 |
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