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Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus

We are extending the Cre/loxP site-specific recombination system to pigs, focussing on conditional and tissue-specific expression of oncogenic mutations to model human cancers. Identifying the location, pattern and extent of Cre recombination in vivo is an important aspect of this technology. Here w...

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Detalles Bibliográficos
Autores principales:	Li, Shun, Flisikowska, Tatiana, Kurome, Mayuko, Zakhartchenko, Valeri, Kessler, Barbara, Saur, Dieter, Kind, Alexander, Wolf, Eckhard, Flisikowski, Krzysztof, Schnieke, Angelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099177/ https://www.ncbi.nlm.nih.gov/pubmed/25025770 http://dx.doi.org/10.1371/journal.pone.0102455

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