Identification of Pre-Erythrocytic Malaria Antigens That Target Hepatocytes for Killing In Vivo and Contribute to Protection Elicited by Whole-Parasite Vaccination

Pre-erythrocytic malaria vaccines, including those based on whole-parasite approaches, have shown protective efficacy in animal and human studies. However few pre-erythocytic antigens other than the immunodominant circumsporozoite protein (CSP) have been studied in depth with the goal of developing...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Keitany, Gladys J., Peng, Xiaohong, Gibson, Claire, Mohar, Isaac, Vignali, Marissa, Crispe, Ian N., Huang, Fusheng, Wang, Ruobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099202/
https://www.ncbi.nlm.nih.gov/pubmed/25025375
http://dx.doi.org/10.1371/journal.pone.0102225

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