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Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells
Synthetic antagonists of the nuclear receptor PPARγ such as GW9662 are widely used to elucidate receptor-mediated ligand effects. In addition and complementary to recent work, we examined whether GW9662 is suitable to serve for mechanistic investigation in T-helper cells. Human peripheral blood mono...
Autores principales: | Jaudszus, Anke, Lorkowski, Stefan, Gruen, Michael, Roth, Alexander, Jahreis, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099290/ https://www.ncbi.nlm.nih.gov/pubmed/25054074 http://dx.doi.org/10.1155/2014/149628 |
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