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Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal
BACKGROUND/AIMS: A revised classification system for renal dysfunction in patients with cirrhosis was proposed by the Acute Dialysis Quality Initiative and the International Ascites Club Working Group in 2011. The aim of this study was to determine the prevalence of renal dysfunction according to th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Association for the Study of the Liver
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099334/ https://www.ncbi.nlm.nih.gov/pubmed/25032185 http://dx.doi.org/10.3350/cmh.2014.20.2.185 |
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author | Choi, Yun Jung Kim, Jeong Han Koo, Ja Kyung Lee, Cho I Lee, Ji Young Yang, Jae Hoon Ko, Soon Young Choe, Won Hyeok Kwon, So Young Lee, Chang Hong |
author_facet | Choi, Yun Jung Kim, Jeong Han Koo, Ja Kyung Lee, Cho I Lee, Ji Young Yang, Jae Hoon Ko, Soon Young Choe, Won Hyeok Kwon, So Young Lee, Chang Hong |
author_sort | Choi, Yun Jung |
collection | PubMed |
description | BACKGROUND/AIMS: A revised classification system for renal dysfunction in patients with cirrhosis was proposed by the Acute Dialysis Quality Initiative and the International Ascites Club Working Group in 2011. The aim of this study was to determine the prevalence of renal dysfunction according to the criteria in this proposal. METHODS: The medical records of cirrhotic patients who were admitted to Konkuk University Hospital between 2006 and 2010 were reviewed retrospectively. The data obtained at first admission were collected. Acute kidney injury (AKI) and chronic kidney disease (CKD) were defined using the proposed diagnostic criteria of kidney dysfunction in cirrhosis. RESULTS: Six hundred and forty-three patients were admitted, of whom 190 (29.5%), 273 (42.5%), and 180 (28.0%) were Child-Pugh class A, B, and C, respectively. Eighty-three patients (12.9%) were diagnosed with AKI, the most common cause for which was dehydration (30 patients). Three patients had hepatorenal syndrome type 1 and 26 patients had prerenal-type AKI caused by volume deficiency after variceal bleeding. In addition, 22 patients (3.4%) were diagnosed with CKD, 1 patient with hepatorenal syndrome type 2, and 3 patients (0.5%) with AKI on CKD. CONCLUSIONS: Both AKI and CKD are common among hospitalized cirrhotic patients, and often occur simultaneously (16.8%). The most common type of renal dysfunction was AKI (12.9%). Diagnosis of type 2 hepatorenal syndrome remains difficult. A prospective cohort study is warranted to evaluate the clinical course in cirrhotic patients with renal dysfunction. |
format | Online Article Text |
id | pubmed-4099334 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Association for the Study of the Liver |
record_format | MEDLINE/PubMed |
spelling | pubmed-40993342014-07-16 Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal Choi, Yun Jung Kim, Jeong Han Koo, Ja Kyung Lee, Cho I Lee, Ji Young Yang, Jae Hoon Ko, Soon Young Choe, Won Hyeok Kwon, So Young Lee, Chang Hong Clin Mol Hepatol Original Article BACKGROUND/AIMS: A revised classification system for renal dysfunction in patients with cirrhosis was proposed by the Acute Dialysis Quality Initiative and the International Ascites Club Working Group in 2011. The aim of this study was to determine the prevalence of renal dysfunction according to the criteria in this proposal. METHODS: The medical records of cirrhotic patients who were admitted to Konkuk University Hospital between 2006 and 2010 were reviewed retrospectively. The data obtained at first admission were collected. Acute kidney injury (AKI) and chronic kidney disease (CKD) were defined using the proposed diagnostic criteria of kidney dysfunction in cirrhosis. RESULTS: Six hundred and forty-three patients were admitted, of whom 190 (29.5%), 273 (42.5%), and 180 (28.0%) were Child-Pugh class A, B, and C, respectively. Eighty-three patients (12.9%) were diagnosed with AKI, the most common cause for which was dehydration (30 patients). Three patients had hepatorenal syndrome type 1 and 26 patients had prerenal-type AKI caused by volume deficiency after variceal bleeding. In addition, 22 patients (3.4%) were diagnosed with CKD, 1 patient with hepatorenal syndrome type 2, and 3 patients (0.5%) with AKI on CKD. CONCLUSIONS: Both AKI and CKD are common among hospitalized cirrhotic patients, and often occur simultaneously (16.8%). The most common type of renal dysfunction was AKI (12.9%). Diagnosis of type 2 hepatorenal syndrome remains difficult. A prospective cohort study is warranted to evaluate the clinical course in cirrhotic patients with renal dysfunction. The Korean Association for the Study of the Liver 2014-06 2014-06-30 /pmc/articles/PMC4099334/ /pubmed/25032185 http://dx.doi.org/10.3350/cmh.2014.20.2.185 Text en Copyright © 2014 by The Korean Association for the Study of the Liver http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Choi, Yun Jung Kim, Jeong Han Koo, Ja Kyung Lee, Cho I Lee, Ji Young Yang, Jae Hoon Ko, Soon Young Choe, Won Hyeok Kwon, So Young Lee, Chang Hong Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title | Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title_full | Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title_fullStr | Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title_full_unstemmed | Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title_short | Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal |
title_sort | prevalence of renal dysfunction in patients with cirrhosis according to adqi-iac working party proposal |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099334/ https://www.ncbi.nlm.nih.gov/pubmed/25032185 http://dx.doi.org/10.3350/cmh.2014.20.2.185 |
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