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Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder
Lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) are highly prevalent in older men. The storage subcategory of LUTS is synonymous with overactive bladder (OAB) syndrome, which is an empirical diagnosis. Traditionally, alpha-blockers are widely prescribed to manage the LUTS...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asian Pacific Prostate Society (APPS)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099395/ https://www.ncbi.nlm.nih.gov/pubmed/25032191 http://dx.doi.org/10.12954/PI.14045 |
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author | Lee, Seung Hwan Lee, Ji Youl |
author_facet | Lee, Seung Hwan Lee, Ji Youl |
author_sort | Lee, Seung Hwan |
collection | PubMed |
description | Lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) are highly prevalent in older men. The storage subcategory of LUTS is synonymous with overactive bladder (OAB) syndrome, which is an empirical diagnosis. Traditionally, alpha-blockers are widely prescribed to manage the LUTS of BPH, although storage symptoms may persist in many men despite treatment. Therefore, because therapies that target the prostate often fail to alleviate storage symptoms, they may not be the appropriate therapy for OAB. In past years, most physicians appeared to give more weight in elderly men to voiding symptoms than to storage symptoms and to be more concerned with initial treatment with anticholinergics for males with storage symptoms. Considering the recent increase in data on the efficacy and safety of combination treatment with alpha receptor antagonists and antimuscarinic agents, the standard pharmacologic treatment of patients with LUTS combined with OAB should be an alpha receptor antagonist and an antimuscarinic agent. Beta-3 adrenoreceptor agonists may also potentially be useful for the treatment of male LUTS combined with OAB. |
format | Online Article Text |
id | pubmed-4099395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Asian Pacific Prostate Society (APPS) |
record_format | MEDLINE/PubMed |
spelling | pubmed-40993952014-07-16 Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder Lee, Seung Hwan Lee, Ji Youl Prostate Int Review Article Lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) are highly prevalent in older men. The storage subcategory of LUTS is synonymous with overactive bladder (OAB) syndrome, which is an empirical diagnosis. Traditionally, alpha-blockers are widely prescribed to manage the LUTS of BPH, although storage symptoms may persist in many men despite treatment. Therefore, because therapies that target the prostate often fail to alleviate storage symptoms, they may not be the appropriate therapy for OAB. In past years, most physicians appeared to give more weight in elderly men to voiding symptoms than to storage symptoms and to be more concerned with initial treatment with anticholinergics for males with storage symptoms. Considering the recent increase in data on the efficacy and safety of combination treatment with alpha receptor antagonists and antimuscarinic agents, the standard pharmacologic treatment of patients with LUTS combined with OAB should be an alpha receptor antagonist and an antimuscarinic agent. Beta-3 adrenoreceptor agonists may also potentially be useful for the treatment of male LUTS combined with OAB. Asian Pacific Prostate Society (APPS) 2014 2014-06-30 /pmc/articles/PMC4099395/ /pubmed/25032191 http://dx.doi.org/10.12954/PI.14045 Text en Copyright © 2014 Asian Pacific Prostate Society (APPS) This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Lee, Seung Hwan Lee, Ji Youl Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title | Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title_full | Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title_fullStr | Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title_full_unstemmed | Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title_short | Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
title_sort | current role of treatment in men with lower urinary tract symptoms combined with overactive bladder |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099395/ https://www.ncbi.nlm.nih.gov/pubmed/25032191 http://dx.doi.org/10.12954/PI.14045 |
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