Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development

Calcium-dependent protein kinases (PKCs) function in a myriad of cellular processes, including cell-cycle regulation, proliferation, hematopoietic stem cell differentiation, apoptosis, and malignant transformation. PKC inhibitors, when targeted to these pathways, have demonstrated efficacy against s...

Descripción completa

Detalles Bibliográficos
Autores principales: Mencalha, André L, Corrêa, Stephany, Abdelhay, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099416/
https://www.ncbi.nlm.nih.gov/pubmed/25045273
http://dx.doi.org/10.2147/OTT.S64303

Ejemplares similares

Ejemplares similares