Cargando…
Functional crosstalk between the mitochondrial PTP and K(ATP) channels determine arrhythmic vulnerability to oxidative stress
Background: Mitochondrial permeability transition pore (mPTP) opening is a terminal event leading to mitochondrial dysfunction and cell death under conditions of oxidative stress (OS). However, mPTP blockade with cyclosporine A (CsA) has shown variable efficacy in limiting post-ischemic dysfunction...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099963/ https://www.ncbi.nlm.nih.gov/pubmed/25076913 http://dx.doi.org/10.3389/fphys.2014.00264 |