Cargando…
Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy
Help seeking (HS) is a core coping strategy that is directed towards obtaining support, advice, or assistance as means of managing stress. Women have been found to use more HS than men. Neural correlates of sex differences have also been reported in prefrontal-limbic system (PLS) regions that are li...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099976/ https://www.ncbi.nlm.nih.gov/pubmed/25027617 http://dx.doi.org/10.1038/srep05700 |
_version_ | 1782326586499923968 |
---|---|
author | Li, Hai-Jiang Sun, Jiang-Zhou Zhang, Qing-Lin Wei, Dong-Tao Li, Wen-Fu Jackson, Todd Hitchman, Glenn Qiu, Jiang |
author_facet | Li, Hai-Jiang Sun, Jiang-Zhou Zhang, Qing-Lin Wei, Dong-Tao Li, Wen-Fu Jackson, Todd Hitchman, Glenn Qiu, Jiang |
author_sort | Li, Hai-Jiang |
collection | PubMed |
description | Help seeking (HS) is a core coping strategy that is directed towards obtaining support, advice, or assistance as means of managing stress. Women have been found to use more HS than men. Neural correlates of sex differences have also been reported in prefrontal-limbic system (PLS) regions that are linked to stress and coping, yet structural differences between men and women relating to HS in the PLS are still unknown. Thus, the association between gray matter volume (GMV) and HS was investigated using voxel-based morphometry (VBM) in a large healthy sample (126 men and 156 women). Results indicated women reported more HS than men did. VBM results showed that the relation between HS scores and GMV differed between men and women in regions of the bilateral orbitofrontal cortex extending to the subgenual anterior cingulate cortex(OFC/sgACC). Among women, higher HS scores were associated with smaller GMV in these areas while a positive correlation between GMV and HS scores was observed among men. These results remained significant after controlling for general intelligence, stress, anxiety and depression. Thus, this study suggested that structural differences between men and women are correlated to characteristic brain regions known to be involved in the PLS which is considered critical in stress regulation. |
format | Online Article Text |
id | pubmed-4099976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-40999762014-07-16 Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy Li, Hai-Jiang Sun, Jiang-Zhou Zhang, Qing-Lin Wei, Dong-Tao Li, Wen-Fu Jackson, Todd Hitchman, Glenn Qiu, Jiang Sci Rep Article Help seeking (HS) is a core coping strategy that is directed towards obtaining support, advice, or assistance as means of managing stress. Women have been found to use more HS than men. Neural correlates of sex differences have also been reported in prefrontal-limbic system (PLS) regions that are linked to stress and coping, yet structural differences between men and women relating to HS in the PLS are still unknown. Thus, the association between gray matter volume (GMV) and HS was investigated using voxel-based morphometry (VBM) in a large healthy sample (126 men and 156 women). Results indicated women reported more HS than men did. VBM results showed that the relation between HS scores and GMV differed between men and women in regions of the bilateral orbitofrontal cortex extending to the subgenual anterior cingulate cortex(OFC/sgACC). Among women, higher HS scores were associated with smaller GMV in these areas while a positive correlation between GMV and HS scores was observed among men. These results remained significant after controlling for general intelligence, stress, anxiety and depression. Thus, this study suggested that structural differences between men and women are correlated to characteristic brain regions known to be involved in the PLS which is considered critical in stress regulation. Nature Publishing Group 2014-07-16 /pmc/articles/PMC4099976/ /pubmed/25027617 http://dx.doi.org/10.1038/srep05700 Text en Copyright © 2014, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-sa/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ |
spellingShingle | Article Li, Hai-Jiang Sun, Jiang-Zhou Zhang, Qing-Lin Wei, Dong-Tao Li, Wen-Fu Jackson, Todd Hitchman, Glenn Qiu, Jiang Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title | Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title_full | Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title_fullStr | Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title_full_unstemmed | Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title_short | Neuroanatomical Differences between Men and Women in Help-Seeking Coping Strategy |
title_sort | neuroanatomical differences between men and women in help-seeking coping strategy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099976/ https://www.ncbi.nlm.nih.gov/pubmed/25027617 http://dx.doi.org/10.1038/srep05700 |
work_keys_str_mv | AT lihaijiang neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT sunjiangzhou neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT zhangqinglin neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT weidongtao neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT liwenfu neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT jacksontodd neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT hitchmanglenn neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy AT qiujiang neuroanatomicaldifferencesbetweenmenandwomeninhelpseekingcopingstrategy |