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Computational and Experimental Approaches to Reveal the Effects of Single Nucleotide Polymorphisms with Respect to Disease Diagnostics

DNA mutations are the cause of many human diseases and they are the reason for natural differences among individuals by affecting the structure, function, interactions, and other properties of DNA and expressed proteins. The ability to predict whether a given mutation is disease-causing or harmless...

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Detalles Bibliográficos
Autores principales:	Kucukkal, Tugba G., Yang, Ye, Chapman, Susan C., Cao, Weiguo, Alexov, Emil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100115/ https://www.ncbi.nlm.nih.gov/pubmed/24886813 http://dx.doi.org/10.3390/ijms15069670

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