Cargando…

SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imag...

Descripción completa

Detalles Bibliográficos
Autores principales: Palumbo, Barbara, Buresta, Tommaso, Nuvoli, Susanna, Spanu, Angela, Schillaci, Orazio, Fravolini, Mario Luca, Palumbo, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100127/
https://www.ncbi.nlm.nih.gov/pubmed/24897023
http://dx.doi.org/10.3390/ijms15069878
_version_ 1782326617436061696
author Palumbo, Barbara
Buresta, Tommaso
Nuvoli, Susanna
Spanu, Angela
Schillaci, Orazio
Fravolini, Mario Luca
Palumbo, Isabella
author_facet Palumbo, Barbara
Buresta, Tommaso
Nuvoli, Susanna
Spanu, Angela
Schillaci, Orazio
Fravolini, Mario Luca
Palumbo, Isabella
author_sort Palumbo, Barbara
collection PubMed
description Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed.
format Online
Article
Text
id pubmed-4100127
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-41001272014-07-16 SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases Palumbo, Barbara Buresta, Tommaso Nuvoli, Susanna Spanu, Angela Schillaci, Orazio Fravolini, Mario Luca Palumbo, Isabella Int J Mol Sci Review Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed. MDPI 2014-06-03 /pmc/articles/PMC4100127/ /pubmed/24897023 http://dx.doi.org/10.3390/ijms15069878 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Palumbo, Barbara
Buresta, Tommaso
Nuvoli, Susanna
Spanu, Angela
Schillaci, Orazio
Fravolini, Mario Luca
Palumbo, Isabella
SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title_full SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title_fullStr SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title_full_unstemmed SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title_short SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases
title_sort spect and pet serve as molecular imaging techniques and in vivo biomarkers for brain metastases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100127/
https://www.ncbi.nlm.nih.gov/pubmed/24897023
http://dx.doi.org/10.3390/ijms15069878
work_keys_str_mv AT palumbobarbara spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT burestatommaso spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT nuvolisusanna spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT spanuangela spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT schillaciorazio spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT fravolinimarioluca spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases
AT palumboisabella spectandpetserveasmolecularimagingtechniquesandinvivobiomarkersforbrainmetastases