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Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition

Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was in...

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Detalles Bibliográficos
Autores principales: Liang, Yongqiang, Li, Haoyan, Xu, Jiang, Li, Xin, Qi, Mengchun, Hu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100132/
https://www.ncbi.nlm.nih.gov/pubmed/24901526
http://dx.doi.org/10.3390/ijms15069952
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author Liang, Yongqiang
Li, Haoyan
Xu, Jiang
Li, Xin
Qi, Mengchun
Hu, Min
author_facet Liang, Yongqiang
Li, Haoyan
Xu, Jiang
Li, Xin
Qi, Mengchun
Hu, Min
author_sort Liang, Yongqiang
collection PubMed
description Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy, and the cytocompatibility and bioactivity of the strontium-doped brushite coatings were evaluated using cultured osteoblasts. Osteoblast proliferation was enhanced by the addition of strontium, suggesting a possible mechanism by which strontium incorporation in brushite coatings increased bone formation surrounding the implants. Cell growth was also strongly influenced by the composition of the deposited coatings, with a 10% Sr-doped brushite coating inducing the greatest amount of bone formation among the tested materials.
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spelling pubmed-41001322014-07-16 Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition Liang, Yongqiang Li, Haoyan Xu, Jiang Li, Xin Qi, Mengchun Hu, Min Int J Mol Sci Article Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy, and the cytocompatibility and bioactivity of the strontium-doped brushite coatings were evaluated using cultured osteoblasts. Osteoblast proliferation was enhanced by the addition of strontium, suggesting a possible mechanism by which strontium incorporation in brushite coatings increased bone formation surrounding the implants. Cell growth was also strongly influenced by the composition of the deposited coatings, with a 10% Sr-doped brushite coating inducing the greatest amount of bone formation among the tested materials. MDPI 2014-06-04 /pmc/articles/PMC4100132/ /pubmed/24901526 http://dx.doi.org/10.3390/ijms15069952 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Liang, Yongqiang
Li, Haoyan
Xu, Jiang
Li, Xin
Qi, Mengchun
Hu, Min
Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title_full Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title_fullStr Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title_full_unstemmed Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title_short Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition
title_sort morphology, composition, and bioactivity of strontium-doped brushite coatings deposited on titanium implants via electrochemical deposition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100132/
https://www.ncbi.nlm.nih.gov/pubmed/24901526
http://dx.doi.org/10.3390/ijms15069952
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