Cargando…

Cytotoxic Autophagy in Cancer Therapy

Autophagy is a process of cellular self-digestion, whereby the cell degrades subcellular materials in order to generate energy and metabolic precursors in order to prolong survival, classically under conditions of nutrient deprivation. Autophagy can also involve the degradation of damaged or aged or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Khushboo, Le, Ngoc, Alotaibi, Moureq, Gewirtz, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100138/ https://www.ncbi.nlm.nih.gov/pubmed/24905404 http://dx.doi.org/10.3390/ijms150610034

Ejemplares similares

Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy
por: Saleh, Tareq, et al.
Publicado: (2020)

Autophagy and radiosensitization in cancer
por: Sharma, Khushboo, et al.
Publicado: (2014)

Cytoprotective, Cytotoxic and Cytostatic Roles of Autophagy in Response to BET Inhibitors
por: Elshazly, Ahmed M., et al.
Publicado: (2023)

The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy
por: Xu, Jingwen, et al.
Publicado: (2022)

Is Autophagy Always a Barrier to Cisplatin Therapy?
por: Xu, Jingwen, et al.
Publicado: (2022)

The Cytoprotective Role of Autophagy in Response to BRAF-Targeted Therapies
por: Elshazly, Ahmed M., et al.
Publicado: (2023)

Making the Case for Autophagy Inhibition as a Therapeutic Strategy in Combination with Androgen-Targeted Therapies in Prostate Cancer
por: Elshazly, Ahmed M., et al.
Publicado: (2023)

The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer
por: Gewirtz, David A.
Publicado: (2020)

Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells
por: Saleh, Tareq, et al.
Publicado: (2022)

Therapeutic Potential for Targeting Autophagy in ER+ Breast Cancer
por: Finnegan, Ryan M., et al.
Publicado: (2022)

Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
por: Elshazly, Ahmed M., et al.
Publicado: (2023)

A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy
por: Alotaibi, Moureq Rashed, et al.
Publicado: (2019)

Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance
por: Xu, Jingwen, et al.
Publicado: (2020)

Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐X(L)–BAX interaction
por: Saleh, Tareq, et al.
Publicado: (2020)

Is autophagy induction by PARP inhibitors a target for therapeutic benefit?
por: ELSHAZLY, AHMED M., et al.
Publicado: (2022)

Senolytics for Cancer Therapy: Is All that Glitters Really Gold?
por: Carpenter, Valerie J., et al.
Publicado: (2021)

An overview of resistance to Human epidermal growth factor receptor 2 (Her2) targeted therapies in breast cancer
por: Elshazly, Ahmed M., et al.
Publicado: (2022)

Autophagy and Breast Cancer: Connected in Growth, Progression, and Therapy
por: Wu, Qitong, et al.
Publicado: (2023)

Editorial: Risks and Benefits of Adjuvants to Cancer Therapies
por: Dong, Peixin, et al.
Publicado: (2022)

Autophagy Modulators in Cancer Therapy
por: Buzun, Kamila, et al.
Publicado: (2021)

Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells
por: As Sobeai, Homood M., et al.
Publicado: (2022)

Cytotoxic and targeted therapy for hereditary cancers
por: Iyevleva, Aglaya G., et al.
Publicado: (2016)

Ras and autophagy in cancer development and therapy
por: Schmukler, Eran, et al.
Publicado: (2014)

Antidepressants as Autophagy Modulators for Cancer Therapy
por: He, Leping, et al.
Publicado: (2023)

The Combination of Radiation with PARP Inhibition Enhances Senescence and Sensitivity to the Senolytic, Navitoclax, in Triple Negative Breast Tumor Cells
por: Softah, Abrar, et al.
Publicado: (2023)

Enhancing Anti-Cancer Therapy with Selective Autophagy Inhibitors by Targeting Protective Autophagy
por: Lee, Min Ju, et al.
Publicado: (2023)

Modulating autophagy: a strategy for cancer therapy
por: Li, Jun-Lin, et al.
Publicado: (2011)

Autophagy in Prostate Cancer and Androgen Suppression Therapy
por: Ziparo, Elio, et al.
Publicado: (2013)

Impact of Autophagy in Oncolytic Adenoviral Therapy for Cancer
por: Tazawa, Hiroshi, et al.
Publicado: (2017)

Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy
por: Silva, Valdenizia R., et al.
Publicado: (2020)

Regulation of Apoptosis by Autophagy to Enhance Cancer Therapy
por: Tompkins, Kenneth D., et al.
Publicado: (2019)

SCD1, autophagy and cancer: implications for therapy
por: Ascenzi, Francesca, et al.
Publicado: (2021)

Autophagy in Cisplatin Nephrotoxicity during Cancer Therapy
por: Hu, Xiaoru, et al.
Publicado: (2021)

Inhibiting autophagy increases epirubicin's cytotoxicity in breast cancer cells
por: Guo, Wei, et al.
Publicado: (2016)

Selective Autophagy Regulates Cell Cycle in Cancer Therapy
por: Zheng, Kai, et al.
Publicado: (2019)

Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer
por: Gąsiorkiewicz, Bartosz Mateusz, et al.
Publicado: (2020)

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy
por: Vitto, Veronica Angela Maria, et al.
Publicado: (2022)

Redox Regulation of Autophagy in Cancer: Mechanism, Prevention and Therapy
por: He, Jingqiu, et al.
Publicado: (2022)

The role of autophagy in tumour development and cancer therapy
por: Rosenfeldt, Mathias T., et al.
Publicado: (2009)

Autophagy and intermittent fasting: the connection for cancer therapy?
por: Antunes, Fernanda, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7q0okpr8dprq82fnleqpv4m6l3