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Thoracic amyloidomas: Two case reports of an evasive diagnosis

Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for tr...

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Detalles Bibliográficos
Autores principales: Cresner, Rosie, Mahmood, Shameem, Chen, Jane, Rowan, Camilla, Wechalekar, Ashutosh D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100224/
https://www.ncbi.nlm.nih.gov/pubmed/25057399
http://dx.doi.org/10.1177/2054270414527280
Descripción
Sumario:Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for treatment of symptoms. We report two cases of amyloidomas, which are rare entities characterised by large local amyloid deposits. These can occur in the upper respiratory tract, soft tissues and central nervous system.(1)