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Thoracic amyloidomas: Two case reports of an evasive diagnosis

Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for tr...

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Autores principales: Cresner, Rosie, Mahmood, Shameem, Chen, Jane, Rowan, Camilla, Wechalekar, Ashutosh D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100224/
https://www.ncbi.nlm.nih.gov/pubmed/25057399
http://dx.doi.org/10.1177/2054270414527280
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author Cresner, Rosie
Mahmood, Shameem
Chen, Jane
Rowan, Camilla
Wechalekar, Ashutosh D
author_facet Cresner, Rosie
Mahmood, Shameem
Chen, Jane
Rowan, Camilla
Wechalekar, Ashutosh D
author_sort Cresner, Rosie
collection PubMed
description Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for treatment of symptoms. We report two cases of amyloidomas, which are rare entities characterised by large local amyloid deposits. These can occur in the upper respiratory tract, soft tissues and central nervous system.(1)
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spelling pubmed-41002242014-07-23 Thoracic amyloidomas: Two case reports of an evasive diagnosis Cresner, Rosie Mahmood, Shameem Chen, Jane Rowan, Camilla Wechalekar, Ashutosh D JRSM Open Case Reports Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for treatment of symptoms. We report two cases of amyloidomas, which are rare entities characterised by large local amyloid deposits. These can occur in the upper respiratory tract, soft tissues and central nervous system.(1) SAGE Publications 2014-05-06 /pmc/articles/PMC4100224/ /pubmed/25057399 http://dx.doi.org/10.1177/2054270414527280 Text en © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Case Reports
Cresner, Rosie
Mahmood, Shameem
Chen, Jane
Rowan, Camilla
Wechalekar, Ashutosh D
Thoracic amyloidomas: Two case reports of an evasive diagnosis
title Thoracic amyloidomas: Two case reports of an evasive diagnosis
title_full Thoracic amyloidomas: Two case reports of an evasive diagnosis
title_fullStr Thoracic amyloidomas: Two case reports of an evasive diagnosis
title_full_unstemmed Thoracic amyloidomas: Two case reports of an evasive diagnosis
title_short Thoracic amyloidomas: Two case reports of an evasive diagnosis
title_sort thoracic amyloidomas: two case reports of an evasive diagnosis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100224/
https://www.ncbi.nlm.nih.gov/pubmed/25057399
http://dx.doi.org/10.1177/2054270414527280
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