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Attenuation of Immune-Mediated Influenza Pneumonia by Targeting the Inducible Co-Stimulator (ICOS) Molecule on T Cells

Inducible Co-stimulator (ICOS) plays a critical role in mediating T cell differentiation and function and is considered a key player in balancing T effector and T regulatory (T(reg)) cell responses. Here we show that activation of the ICOS signalling pathway during acute influenza A virus (IAV) infe...

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Detalles Bibliográficos
Autores principales:	Sakthivel, Priya, Gereke, Marcus, Breithaupt, Angele, Fuchs, Dietmar, Gigliotti, Luca, Gruber, Achim D., Dianzani, Umberto, Bruder, Dunja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100737/ https://www.ncbi.nlm.nih.gov/pubmed/25029240 http://dx.doi.org/10.1371/journal.pone.0100970

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