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DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells
Supporting cells (SCs) of the cochlear (auditory) and vestibular (balance) organs hold promise as a platform for therapeutic regeneration of the sensory hair cells. Prior data have shown proliferative restrictions of adult SCs forced to re-enter the cell cycle. By comparing juvenile and adult SCs in...
Autores principales: | Laos, Maarja, Anttonen, Tommi, Kirjavainen, Anna, Hällström, Taija af, Laiho, Marikki, Pirvola, Ulla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100811/ https://www.ncbi.nlm.nih.gov/pubmed/25063730 |
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