Cargando…

A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations

Tetracycline-based matrix metalloproteinase- (MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic MMP-inhibitor not based on an antibiotic. To induce experimental periodontitis,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elburki, Muna S., Rossa, Carlos, Guimaraes, Morgana R., Goodenough, Mark, Lee, Hsi-Ming, Curylofo, Fabiana A., Zhang, Yu, Johnson, Francis, Golub, Lorne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101223/ https://www.ncbi.nlm.nih.gov/pubmed/25104884 http://dx.doi.org/10.1155/2014/959471

Ejemplares similares

A Novel Chemically Modified Curcumin “Normalizes” Wound-Healing in Rats with Experimentally Induced Type I Diabetes: Initial Studies
por: Zhang, Yazhou, et al.
Publicado: (2016)

Enhanced efficacy of chemically modified curcumin in experimental periodontitis: systemic implications
por: Wang, Howard H, et al.
Publicado: (2019)

Chemically-Modified Curcumin 2.24: A Novel Systemic Therapy for Natural Periodontitis in Dogs
por: Deng, Jie, et al.
Publicado: (2020)

Inhibition of anthrax lethal factor by curcumin and chemically modified curcumin derivatives
por: Antonelli, Anthony C., et al.
Publicado: (2014)

A Novel Modified-Curcumin Promotes Resolvin-Like Activity and Reduces Bone Loss in Diabetes-Induced Experimental Periodontitis
por: Deng, Jie, et al.
Publicado: (2021)

The Maximum-Tolerated Dose and Pharmacokinetics of a Novel Chemically Modified Curcumin in Rats
por: Bhatt, Heta Dinesh, et al.
Publicado: (2022)

4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation
por: Gu, Ying, et al.
Publicado: (2013)

Enhanced Efficacy of Chemically Modified Curcumin in Experimental Periodontitis: Systemic Implications [Corrigendum]
Publicado: (2020)

A novel modified-curcumin 2.24 resolves inflammation by promoting M2 macrophage polarization
por: Deng, Jie, et al.
Publicado: (2023)

Local administration of curcumin-loaded nanoparticles effectively inhibits inflammation and bone resorption associated with experimental periodontal disease
por: Zambrano, Laura M. G., et al.
Publicado: (2018)

Periodontal therapeutics: Current host‐modulation agents and future directions
por: Golub, Lorne M., et al.
Publicado: (2019)

Does Chemically Modified Curcumin Control the Progression of Periodontitis? A Systematic Review
por: Dhaifullah, Esam, et al.
Publicado: (2021)

Evaluation of the efficacy of 2% curcumin gel in the treatment of experimental periodontitis
por: Hosadurga, Rajesh Ramesh, et al.
Publicado: (2014)

Protective effect and related mechanisms of curcumin in rat experimental periodontitis
por: Xiao, Chang-Jie, et al.
Publicado: (2018)

Pleiotropy of chemically modified tetracycline in periodontitis
por: Agarwal, Ashish
Publicado: (2013)

Topical application of bFGF on acid-conditioned and non-conditioned dentin: effect on cell proliferation and gene expression in cells relevant for periodontal regeneration
por: Rocha, Fernanda Regina Godoy, et al.
Publicado: (2017)

Antioxidant Effects of Curcumin Gel in Experimental Induced Diabetes and Periodontitis in Rats
por: Mohammad, Chenar Anwar, et al.
Publicado: (2022)

Novel Chemically Modified Curcumin (CMC) Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis in B16F10 Mouse Melanoma Cells
por: Goenka, Shilpi, et al.
Publicado: (2021)

The Link Between Periodontitis and Rheumatoid Arthritis: A Periodontist’s Perspective
por: Payne, Jeffrey B., et al.
Publicado: (2014)

The Antioxidant Effect of Curcumin and Rutin on Oxidative Stress Biomarkers in Experimentally Induced Periodontitis in Hyperglycemic Wistar Rats
por: Iova, Gilda M., et al.
Publicado: (2021)

Effects of curcumin gel on osteoclastogenic bone markers in experimental periodontitis and alveolar bone loss in wistar rats
por: Sha, Aram Mohammed, et al.
Publicado: (2021)

Effect of 1% curcumin gel on myeloperoxidase activity in GCF and periodontal status in the initial phase of orthodontic tooth movement
por: Samita,, et al.
Publicado: (2022)

A modified method for constructing experimental rat periodontitis model
por: Zhang, Xuyang, et al.
Publicado: (2023)

Chemically modified tetracyclines: Novel therapeutic agents in the management of chronic periodontitis
por: Agnihotri, Rupali, et al.
Publicado: (2012)

Curcumin Attenuates Periodontal Injury via Inhibiting Ferroptosis of Ligature-Induced Periodontitis in Mice
por: Wang, Yawei, et al.
Publicado: (2023)

Treatment of experimental periodontal disease by laser therapy in simvastatin-modified rats
por: SWERTS, Andressa Araújo, et al.
Publicado: (2017)

Corrigendum: A modified method for constructing experimental rat periodontitis model
por: Zhang, Xuyang, et al.
Publicado: (2023)

Effect of Curcumin gel on inflammatory and anti-inflammatory biomarkers in experimental induced periodontitis in rats: a biochemical and immunological study
por: Mohammad, Chenar Anwar, et al.
Publicado: (2023)

Efficacy of a Novel Pleiotropic MMP-Inhibitor, CMC2.24, in a Long-Term Diabetes Rat Model with Severe Hyperglycemia-Induced Oral Bone Loss
por: Bhatt, Heta Dinesh, et al.
Publicado: (2023)

Novel Chemically Modified Curcumin (CMC) Analogs Exhibit Anti-Melanogenic Activity in Primary Human Melanocytes
por: Goenka, Shilpi, et al.
Publicado: (2021)

Systemic Chemical Desensitization of Peptidergic Sensory Neurons with Resiniferatoxin Inhibits Experimental Periodontitis
por: Breivik, Torbjørn, et al.
Publicado: (2011)

Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients
por: Ravishankar, P. L., et al.
Publicado: (2017)

An in vitro evaluation of cytotoxicity of curcumin against human periodontal ligament fibroblasts
por: Mandroli, Praveenkumar S., et al.
Publicado: (2019)

Oral nano‐curcumin on gingival inflammation in patients with gingivitis and mild periodontitis
por: Malekzadeh, Meisam, et al.
Publicado: (2020)

Liposomal Curcumin is Better than Curcumin to Alleviate Complications in Experimental Diabetic Mellitus
por: Bulboacă, Adriana Elena, et al.
Publicado: (2019)

Experimental dissection of flagellar surface motility in chlamydomonas
por: Hoffman, JL, et al.
Publicado: (1980)

Evaluation of a curcumin-containing mucoadhesive film for periodontal postsurgical pain control
por: Anil, Anu, et al.
Publicado: (2019)

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis
por: Nasra, Maha M. A., et al.
Publicado: (2017)

Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration
por: Chang, Mingxiang, et al.
Publicado: (2020)

Suppression of Experimental Choroidal Neovascularization by Curcumin in Mice
por: Xie, Ping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_j4qictm206s0qli80br4hkoqi6