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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer
The integration of targeted agents to standard cytotoxic regimens has improved outcomes for patients with colorectal cancer (CRC) over recent years; however this malignancy remains the second leading cause of cancer mortality in industrialized countries. Small molecule inhibitors of heat shock prote...
Autores principales: | He, Suqin, Smith, Donald L., Sequeira, Manuel, Sang, Jim, Bates, Richard C., Proia, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101249/ https://www.ncbi.nlm.nih.gov/pubmed/24682747 http://dx.doi.org/10.1007/s10637-014-0095-4 |
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