Cargando…

Hippo Signaling Mediates Proliferation, Invasiveness, and Metastatic Potential of Clear Cell Renal Cell Carcinoma()

Recent work has identified dysfunctional Hippo signaling to be involved in maintenance and progression of various human cancers, although data on clear cell renal cell carcinoma (ccRCC) have been limited. Here, we provide evidence implicating aberrant Hippo signaling in ccRCC proliferation, invasive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schütte, Ute, Bisht, Savita, Heukamp, Lukas C., Kebschull, Moritz, Florin, Alexandra, Haarmann, Jens, Hoffmann, Per, Bendas, Gerd, Buettner, Reinhard, Brossart, Peter, Feldmann, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101344/ https://www.ncbi.nlm.nih.gov/pubmed/24913676 http://dx.doi.org/10.1016/j.tranon.2014.02.005

Ejemplares similares

Cyclin-Dependent Kinase 5 (CDK5) Controls Melanoma Cell Motility, Invasiveness, and Metastatic Spread—Identification of a Promising Novel therapeutic target()
por: Bisht, Savita, et al.
Publicado: (2015)

A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies
por: Bisht, Savita, et al.
Publicado: (2016)

EF24 Suppresses Cholangiocellular Carcinoma Progression, Inhibits STAT3 Phosphorylation, and Induces Apoptosis via ROS-Mediated Oxidative Stress
por: Bisht, Savita, et al.
Publicado: (2019)

Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer
por: Lerbs, Tristan, et al.
Publicado: (2017)

A Combined Activity of Thrombin and P-Selectin Is Essential for Platelet Activation by Pancreatic Cancer Cells
por: Haschemi, Reza, et al.
Publicado: (2021)

Cancer Cell Adhesion and Metastasis: Selectins, Integrins, and the Inhibitory Potential of Heparins
por: Bendas, Gerd, et al.
Publicado: (2012)

Tumour cell-activated platelets modulate the immunological activity of CD4(+), CD8(+), and NK cells, which is efficiently antagonized by heparin
por: Gockel, Lukas M., et al.
Publicado: (2022)

Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy
por: Bisht, Savita, et al.
Publicado: (2007)

The Low Molecular Weight Heparin Tinzaparin Attenuates Platelet Activation in Terms of Metastatic Niche Formation by Coagulation-Dependent and Independent Pathways
por: Gockel, Lukas Maria, et al.
Publicado: (2018)

Loss of the Keratin Cytoskeleton Is Not Sufficient to Induce Epithelial Mesenchymal Transition in a Novel KRAS Driven Sporadic Lung Cancer Mouse Model
por: König, Katharina, et al.
Publicado: (2013)

Systemic Therapy of Neuroendocrine Neoplasia: Single Center Experience from a Cohort of 110 Consecutive Cases
por: Mayer, Karin, et al.
Publicado: (2020)

Mixed Response to Ipilimumab in a Melanoma Patient with Brain Metastases: Case Report and Review of the Literature
por: Feldmann, Georg, et al.
Publicado: (2013)

Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin
por: Schwarz, Svenja, et al.
Publicado: (2020)

The mechanisms how heparin affects the tumor cell induced VEGF and chemokine release from platelets to attenuate the early metastatic niche formation
por: Ponert, Jan Moritz, et al.
Publicado: (2018)

The LIM-Only Protein FHL2 Reduces Vascular Lesion Formation Involving Inhibition of Proliferation and Migration of Smooth Muscle Cells
por: Kurakula, Kondababu, et al.
Publicado: (2014)

Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization
por: Jakubzig, Bastian, et al.
Publicado: (2018)

Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway
por: Piva, Maria B. R., et al.
Publicado: (2017)

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas
por: Meder, Lydia, et al.
Publicado: (2015)

Blastic plasmacytoid dendritic-cell neoplasia: a challenging case report
por: Koerber, Ruth-Miriam, et al.
Publicado: (2021)

The GPIb-IX complex on platelets: insight into its novel physiological functions affecting immune surveillance, hepatic thrombopoietin generation, platelet clearance and its relevance for cancer development and metastasis
por: Bendas, Gerd, et al.
Publicado: (2022)

SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway
por: Yin, Lei, et al.
Publicado: (2020)

Hippo inactivation feeds tumor-initiating cells
por: Duss, Stephan, et al.
Publicado: (2012)

Hippo Signal Transduction Mechanisms in T Cell Immunity
por: Bouchard, Antoine, et al.
Publicado: (2020)

Web-based database for the management of tissue specimens in a transregional histological research facility
por: Huss, Sebastian, et al.
Publicado: (2011)

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol
por: Jagannathan, Radhika, et al.
Publicado: (2016)

Biosensor Applications in the Field of Antibiotic Research—A Review of Recent Developments
por: Reder-Christ, Katrin, et al.
Publicado: (2011)

HippoDraw
por: Gravina, M F, et al.
Publicado: (1992)

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras (LSL-G12V) Driven Lung Cancer Mouse Model
por: Meder, Lydia, et al.
Publicado: (2021)

Hippo Pathway in Cancer, towards the Realization of Hippo-Targeted Therapy
por: Hata, Yutaka
Publicado: (2018)

Hippo throws its weight behind migrating cells
por: Leslie, Mitch
Publicado: (2013)

The Role of Hippo Pathway in Cancer Stem Cell Biology
por: Park, Jae Hyung, et al.
Publicado: (2018)

The role of Hippo‐YAP signaling in squamous cell carcinomas
por: Maehama, Tomohiko, et al.
Publicado: (2020)

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms
por: Dobrokhotov, Oleg, et al.
Publicado: (2018)

The Hippo signaling pathway in gastric cancer: Targeting Hippo for GC treatment
por: Cao, Zhifa, et al.
Publicado: (2023)

The clinical relevance of the Hippo pathway in pancreatic ductal adenocarcinoma
por: Drexler, Richard, et al.
Publicado: (2020)

Hippo signaling controls cell cycle and restricts cell plasticity in planarians
por: de Sousa, Nídia, et al.
Publicado: (2018)

Exostosin 1 Knockdown Induces Chemoresistance in MV3 Melanoma Cells by Upregulating JNK and MEK/ERK Signaling
por: Pfeifer, Vladlena, et al.
Publicado: (2023)

Dishevelling Wnt and Hippo
por: Kim, Nam Hee, et al.
Publicado: (2018)

Hippo Signaling in the Endometrium
por: Moon, Sohyeon, et al.
Publicado: (2022)

Tuberous-sclerosis complex-related cell signaling in the pathogenesis of lung cancer
por: Fuchs, Angela, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5niq52k3q4oblrk4g9713tsi04