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Identification of novel therapeutics for complex diseases from genome-wide association data

BACKGROUND: Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively translate this data to the clinic has not kept pace. Over the past 60 years, pharmaceutical companies have successfully demonstrated the safety and efficacy of over 1,200 n...

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Detalles Bibliográficos
Autores principales: Grover, Mani P, Ballouz, Sara, Mohanasundaram, Kaavya A, George, Richard A, H Sherman, Craig D, Crowley, Tamsyn M, Wouters, Merridee A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101352/
https://www.ncbi.nlm.nih.gov/pubmed/25077696
http://dx.doi.org/10.1186/1755-8794-7-S1-S8