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Propofol Exposure in Pregnant Rats Induces Neurotoxicity and Persistent Learning Deficit in the Offspring

Propofol is a general anesthetic widely used in surgical procedures, including those in pregnant women. Preclinical studies suggest that propofol may cause neuronal injury to the offspring of primates if it is administered during pregnancy. However, it is unknown whether those neuronal changes would...

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Detalles Bibliográficos
Autores principales: Xiong, Ming, Li, Jing, Alhashem, Hussain M., Tilak, Vasanti, Patel, Anuradha, Pisklakov, Sergey, Siegel, Allan, Ye, Jiang Hong, Bekker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101482/
https://www.ncbi.nlm.nih.gov/pubmed/24961766
http://dx.doi.org/10.3390/brainsci4020356