Cargando…

Propofol Exposure in Pregnant Rats Induces Neurotoxicity and Persistent Learning Deficit in the Offspring

Propofol is a general anesthetic widely used in surgical procedures, including those in pregnant women. Preclinical studies suggest that propofol may cause neuronal injury to the offspring of primates if it is administered during pregnancy. However, it is unknown whether those neuronal changes would...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Ming, Li, Jing, Alhashem, Hussain M., Tilak, Vasanti, Patel, Anuradha, Pisklakov, Sergey, Siegel, Allan, Ye, Jiang Hong, Bekker, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101482/ https://www.ncbi.nlm.nih.gov/pubmed/24961766 http://dx.doi.org/10.3390/brainsci4020356

Ejemplares similares

Propofol-Induced Neurotoxicity in the Fetal Animal Brain and Developments in Modifying These Effects—An Updated Review of Propofol Fetal Exposure in Laboratory Animal Studies
por: Xiong, Ming, et al.
Publicado: (2016)

Propofol produces neurotoxicity by inducing mitochondrial apoptosis
por: Liang, Yubing, et al.
Publicado: (2022)

Protective Effects of Propofol Against Methamphetamine-induced Neurotoxicity
por: Shokrzadeh, Mohammad, et al.
Publicado: (2015)

Role of ferroptosis in hypoxic preconditioning to reduce propofol neurotoxicity
por: Chen, Jing, et al.
Publicado: (2023)

Neurobiology of Propofol Addiction and Supportive Evidence: What Is the New Development?
por: Xiong, Ming, et al.
Publicado: (2018)

Effect of preconditioning on propofol-induced neurotoxicity during the developmental period
por: Shibuta, Satoshi, et al.
Publicado: (2022)

Monosialoganglioside 1 may alleviate neurotoxicity induced by propofol combined with remifentanil in neural stem cells
por: Lu, Jiang, et al.
Publicado: (2017)

Parallels between attention deficit hyperactivity disorder and behavioral deficits produced by neurotoxic exposure in monkeys.
por: Rice, D C
Publicado: (2000)

Different behavioral effects of neurotoxic dorsal hippocampal lesions placed under either isoflurane or propofol anesthesia
por: Baxter, Mark G, et al.
Publicado: (2008)

A comparative study of propofol, thiopentone sodium, and ketofol as induction agents for electro convulsive therapy
por: Gaddam, Nagraju R., et al.
Publicado: (2021)

Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
por: Rappold, Phillip M., et al.
Publicado: (2014)

Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits
por: Wu, Jing, et al.
Publicado: (2020)

Signaling network between the dysregulated expression of microRNAs and mRNAs in propofol-induced developmental neurotoxicity in mice
por: Jiang, Congshan, et al.
Publicado: (2018)

Etiology of autistic features: the persisting neurotoxic effects of propionic acid
por: El-Ansary, Afaf K, et al.
Publicado: (2012)

Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?
por: Schneider, Jay S.
Publicado: (2023)

Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke
por: Pan, Yuhualei, et al.
Publicado: (2021)

Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway
por: Yang, Yangliang, et al.
Publicado: (2021)

Butyrate Supplementation to Pregnant Mice Elicits Cytoprotection Against Colonic Injury in Offspring
por: Barbian, Maria E., et al.
Publicado: (2022)

Melatonin Administration to Pregnant Ewes for Coccidiosis Control in Their Offspring
por: Bouroutzika, Efterpi, et al.
Publicado: (2023)

Persistent low bispectral index values with propofol in a patient of cirrhosis
por: Khandelwal, Ankur, et al.
Publicado: (2021)

Dose Effects of Oxaliplatin on Persistent and Transient Na(+) Conductances and the Development of Neurotoxicity
por: Park, Susanna B., et al.
Publicado: (2011)

Propofol exposure during early gestation impairs learning and memory in rat offspring by inhibiting the acetylation of histone
por: Lin, Jiamei, et al.
Publicado: (2018)

Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices
por: Berndt, Nikolaus, et al.
Publicado: (2018)

Effect of the pregnant mice with Graves’ disease on thyroid function in the offspring
por: Liu, Qianqi, et al.
Publicado: (2013)

A Transfer of Silver Nanoparticles from Pregnant Rat to Offspring
por: Lee, Yeonjin, et al.
Publicado: (2012)

Influence of isoflurane exposure in pregnant rats on the learning and memory of offsprings
por: Huang, Wei, et al.
Publicado: (2018)

Influenza Vaccination of Pregnant Women and Serious Adverse Events in the Offspring
por: Donzelli, Alberto
Publicado: (2019)

Maternal Diabetes and Postnatal High-Fat Diet on Pregnant Offspring
por: Sinzato, Yuri Karen, et al.
Publicado: (2022)

Risk Assessment for Birth Defects in Offspring of Chinese Pregnant Women
por: Qu, Pengfei, et al.
Publicado: (2022)

Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
por: Perika, Tilak, et al.
Publicado: (2019)

Comparison of electroencephalogram between propofol- and thiopental-induced anesthesia for awareness risk in pregnant women
por: Park, Hee-Sun, et al.
Publicado: (2020)

Protective effect of rosemary on acrylamide motor neurotoxicity in spinal cord of rat offspring: postnatal follow-up study
por: Al-Gholam, Marwa A., et al.
Publicado: (2016)

Maternal Biomarkers of Acetaminophen Use and Offspring Attention Deficit Hyperactivity Disorder
por: Ji, Yuelong, et al.
Publicado: (2018)

Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder
por: Gustavson, Kristin, et al.
Publicado: (2019)

Sex differences in parent–offspring recurrence of attention‐deficit/hyperactivity disorder
por: Solberg, Berit S., et al.
Publicado: (2020)

Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway
por: Xiao, Yong, et al.
Publicado: (2018)

Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways
por: Tu, Youbing, et al.
Publicado: (2019)

Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol-induced neurotoxicity in the hippocampus of neonatal rats
por: Guan, Ruicong, et al.
Publicado: (2019)

Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention‐deficit hyperactivity disorder risk in offspring
por: Haan, Elis, et al.
Publicado: (2021)

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency
por: Reifschneider, Anika, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k43dlhuaop670ngg509ui71437