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Modelling Proteasome and Proteasome Regulator Activities
Proteasomes are key proteases involved in a variety of processes ranging from the clearance of damaged proteins to the presentation of antigens to CD8(+) T-lymphocytes. Which cleavage sites are used within the target proteins and how fast these proteins are degraded have a profound impact on immune...
Autores principales: | Liepe, Juliane, Holzhütter, Herman-Georg, Kloetzel, Peter M., Stumpf, Michael P. H., Mishto, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101499/ https://www.ncbi.nlm.nih.gov/pubmed/24970232 http://dx.doi.org/10.3390/biom4020585 |
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