The common ground of genomics and systems biology

The rise of systems biology is intertwined with that of genomics, yet their primordial relationship to one another is ill-defined. We discuss how the growth of genomics provided a critical boost to the popularity of systems biology. We describe the parts of genomics that share common areas of intere...

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Detalles Bibliográficos
Autores principales: Conesa, Ana, Mortazavi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101703/
https://www.ncbi.nlm.nih.gov/pubmed/25033072
http://dx.doi.org/10.1186/1752-0509-8-S2-S1
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author Conesa, Ana
Mortazavi, Ali
author_facet Conesa, Ana
Mortazavi, Ali
author_sort Conesa, Ana
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description The rise of systems biology is intertwined with that of genomics, yet their primordial relationship to one another is ill-defined. We discuss how the growth of genomics provided a critical boost to the popularity of systems biology. We describe the parts of genomics that share common areas of interest with systems biology today in the areas of gene expression, network inference, chromatin state analysis, pathway analysis, personalized medicine, and upcoming areas of synergy as genomics continues to expand its scope across all biomedical fields.
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spelling pubmed-41017032014-07-18 The common ground of genomics and systems biology Conesa, Ana Mortazavi, Ali BMC Syst Biol Review The rise of systems biology is intertwined with that of genomics, yet their primordial relationship to one another is ill-defined. We discuss how the growth of genomics provided a critical boost to the popularity of systems biology. We describe the parts of genomics that share common areas of interest with systems biology today in the areas of gene expression, network inference, chromatin state analysis, pathway analysis, personalized medicine, and upcoming areas of synergy as genomics continues to expand its scope across all biomedical fields. BioMed Central 2014-03-13 /pmc/articles/PMC4101703/ /pubmed/25033072 http://dx.doi.org/10.1186/1752-0509-8-S2-S1 Text en Copyright © 2014 Conesa and Mortazavi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Conesa, Ana
Mortazavi, Ali
The common ground of genomics and systems biology
title The common ground of genomics and systems biology
title_full The common ground of genomics and systems biology
title_fullStr The common ground of genomics and systems biology
title_full_unstemmed The common ground of genomics and systems biology
title_short The common ground of genomics and systems biology
title_sort common ground of genomics and systems biology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101703/
https://www.ncbi.nlm.nih.gov/pubmed/25033072
http://dx.doi.org/10.1186/1752-0509-8-S2-S1
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