Monoclonal antibody targeting complement C9 binding domain of Trichinella spiralis paramyosin impairs the viability of Trichinella infective larvae in the presence of complement

BACKGROUND: Trichinella spiralis expresses paramyosin (Ts-Pmy) not only as a structural protein but also as an immunomodulator that inhibits host complement as a survival strategy. Previous studies demonstrated that Ts-Pmy bound to complement components C8 and C9 and inhibited the polymerization of...

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Detalles Bibliográficos
Autores principales: Hao, Yuwan, Zhao, Xi, Yang, Jing, Gu, Yuan, Sun, Ran, Zhu, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101707/
https://www.ncbi.nlm.nih.gov/pubmed/24996670
http://dx.doi.org/10.1186/1756-3305-7-313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101707/
https://www.ncbi.nlm.nih.gov/pubmed/24996670
http://dx.doi.org/10.1186/1756-3305-7-313

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