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15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells

The expression of 15-lipoxygenase-1 (15-LOX-1) is downregulated in colon cancer and other major cancers, and 15-LOX-1 reexpression in cancer cells suppresses colonic tumorigenesis. Various lines of evidence indicate that 15-LOX-1 expression suppresses premetastatic stages of colonic tumorigenesis; n...

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Detalles Bibliográficos
Autores principales:	Wu, Yuanqing, Mao, Fei, Zuo, Xiangsheng, Moussalli, Micheline J, Elias, Elias, Xu, Weiguo, Shureiqi, Imad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101738/ https://www.ncbi.nlm.nih.gov/pubmed/24634093 http://dx.doi.org/10.1002/cam4.222

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