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Modeling tandem AAG8-MEK inhibition in melanoma cells
Drug resistance presents a challenge to the treatment of cancer patients, especially for melanomas, most of which are caused by the hyperactivation of MAPK signaling pathway. Innate or acquired drug-resistant relapse calls for the investigation of the resistant mechanisms and new anti-cancer drugs t...
Autores principales: | Sun, Bing, Kawahara, Masahiro, Nagamune, Teruyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101763/ https://www.ncbi.nlm.nih.gov/pubmed/24634165 http://dx.doi.org/10.1002/cam4.233 |
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