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COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients

BACKGROUND: The majority of Osteogenesis Imperfecta (OI) cases are caused by mutations in one of the two genes, COL1A1 and COL1A2 encoding for the two chains that trimerize to form the procollagen 1 molecule. However, alterations in gene expression and microRNAs (miRNAs) are responsible for the regu...

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Detalles Bibliográficos
Autores principales:	Kaneto, Carla M, Lima, Patrícia SP, Zanette, Dalila L, Prata, Karen L, Pina Neto, João M, de Paula, Francisco JA, Silva, Wilson A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101867/ https://www.ncbi.nlm.nih.gov/pubmed/24767406 http://dx.doi.org/10.1186/1471-2350-15-45

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