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The thinning top: why old people have less hair
Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen and colleagues point to an imbalance between stem cell activating and inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted pro...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101907/ https://www.ncbi.nlm.nih.gov/pubmed/25029319 http://dx.doi.org/10.1038/jid.2014.172 |
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author | Reddy, Sashank Garza, Luis A. |
author_facet | Reddy, Sashank Garza, Luis A. |
author_sort | Reddy, Sashank |
collection | PubMed |
description | Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen and colleagues point to an imbalance between stem cell activating and inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal. |
format | Online Article Text |
id | pubmed-4101907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
record_format | MEDLINE/PubMed |
spelling | pubmed-41019072015-02-01 The thinning top: why old people have less hair Reddy, Sashank Garza, Luis A. J Invest Dermatol Article Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen and colleagues point to an imbalance between stem cell activating and inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal. 2014-08 /pmc/articles/PMC4101907/ /pubmed/25029319 http://dx.doi.org/10.1038/jid.2014.172 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Reddy, Sashank Garza, Luis A. The thinning top: why old people have less hair |
title | The thinning top: why old people have less hair |
title_full | The thinning top: why old people have less hair |
title_fullStr | The thinning top: why old people have less hair |
title_full_unstemmed | The thinning top: why old people have less hair |
title_short | The thinning top: why old people have less hair |
title_sort | thinning top: why old people have less hair |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101907/ https://www.ncbi.nlm.nih.gov/pubmed/25029319 http://dx.doi.org/10.1038/jid.2014.172 |
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