Cargando…

Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging

Different treatment interventions induce distinct remodelling of network architecture of entire motor system. Acupuncture has been proved to be of a promising efficacy in motor recovery. However, it is still unclear whether the reorganization of motor-related brain network underlying acupuncture is...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Lijun, Tao, Yin, Wang, Dan, Wang, Jing, Sun, Chuanzhu, Hao, Nongxiao, Chen, Shangjie, Lao, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101930/
https://www.ncbi.nlm.nih.gov/pubmed/25101136
http://dx.doi.org/10.1155/2014/740480
_version_ 1782480977677778944
author Bai, Lijun
Tao, Yin
Wang, Dan
Wang, Jing
Sun, Chuanzhu
Hao, Nongxiao
Chen, Shangjie
Lao, Lixing
author_facet Bai, Lijun
Tao, Yin
Wang, Dan
Wang, Jing
Sun, Chuanzhu
Hao, Nongxiao
Chen, Shangjie
Lao, Lixing
author_sort Bai, Lijun
collection PubMed
description Different treatment interventions induce distinct remodelling of network architecture of entire motor system. Acupuncture has been proved to be of a promising efficacy in motor recovery. However, it is still unclear whether the reorganization of motor-related brain network underlying acupuncture is related with time since stroke and severity of deficit at baseline. The aim of study was to characterize the relation between motor-related brain organization following acupuncture and white matter microstructural changes at an interval of two weeks. We demonstrated that acupuncture induced differential reorganization of motor-related network for stroke patients as time-lapse since stroke. At the baseline, acupuncture can induce the increased functional connectivity between the left primary motor cortex (M1) and the right M1, premotor cortex, supplementary motor area (SMA), thalamus, and cerebellum. After two-week recovery, the increased functional connectivity of the left M1 was more widely distributed and primarily located in the insula, cerebellum, basal ganglia, and SMA. Furthermore, a significant negative relation existed between the FA value in the left M1 at the baseline scanning and node centrality of this region following acupuncture for both baseline and two-week recovery. Our findings may shed a new insight on understanding the reorganization of motor-related theory underlying motor impairments after brain lesions in stroke patients.
format Online
Article
Text
id pubmed-4101930
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-41019302014-08-06 Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging Bai, Lijun Tao, Yin Wang, Dan Wang, Jing Sun, Chuanzhu Hao, Nongxiao Chen, Shangjie Lao, Lixing Evid Based Complement Alternat Med Research Article Different treatment interventions induce distinct remodelling of network architecture of entire motor system. Acupuncture has been proved to be of a promising efficacy in motor recovery. However, it is still unclear whether the reorganization of motor-related brain network underlying acupuncture is related with time since stroke and severity of deficit at baseline. The aim of study was to characterize the relation between motor-related brain organization following acupuncture and white matter microstructural changes at an interval of two weeks. We demonstrated that acupuncture induced differential reorganization of motor-related network for stroke patients as time-lapse since stroke. At the baseline, acupuncture can induce the increased functional connectivity between the left primary motor cortex (M1) and the right M1, premotor cortex, supplementary motor area (SMA), thalamus, and cerebellum. After two-week recovery, the increased functional connectivity of the left M1 was more widely distributed and primarily located in the insula, cerebellum, basal ganglia, and SMA. Furthermore, a significant negative relation existed between the FA value in the left M1 at the baseline scanning and node centrality of this region following acupuncture for both baseline and two-week recovery. Our findings may shed a new insight on understanding the reorganization of motor-related theory underlying motor impairments after brain lesions in stroke patients. Hindawi Publishing Corporation 2014 2014-07-02 /pmc/articles/PMC4101930/ /pubmed/25101136 http://dx.doi.org/10.1155/2014/740480 Text en Copyright © 2014 Lijun Bai et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bai, Lijun
Tao, Yin
Wang, Dan
Wang, Jing
Sun, Chuanzhu
Hao, Nongxiao
Chen, Shangjie
Lao, Lixing
Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title_full Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title_fullStr Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title_full_unstemmed Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title_short Acupuncture Induces Time-Dependent Remodelling Brain Network on the Stable Somatosensory First-Ever Stroke Patients: Combining Diffusion Tensor and Functional MR Imaging
title_sort acupuncture induces time-dependent remodelling brain network on the stable somatosensory first-ever stroke patients: combining diffusion tensor and functional mr imaging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101930/
https://www.ncbi.nlm.nih.gov/pubmed/25101136
http://dx.doi.org/10.1155/2014/740480
work_keys_str_mv AT bailijun acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT taoyin acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT wangdan acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT wangjing acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT sunchuanzhu acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT haonongxiao acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT chenshangjie acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging
AT laolixing acupunctureinducestimedependentremodellingbrainnetworkonthestablesomatosensoryfirsteverstrokepatientscombiningdiffusiontensorandfunctionalmrimaging