MicroRNAs: Novel Players in Cancer Diagnosis and Therapies

First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miR...

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Detalles Bibliográficos
Autores principales: Oom, Aaron L., Humphries, Brock A., Yang, Chengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101974/
https://www.ncbi.nlm.nih.gov/pubmed/25101302
http://dx.doi.org/10.1155/2014/959461
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author Oom, Aaron L.
Humphries, Brock A.
Yang, Chengfeng
author_facet Oom, Aaron L.
Humphries, Brock A.
Yang, Chengfeng
author_sort Oom, Aaron L.
collection PubMed
description First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.
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spelling pubmed-41019742014-08-06 MicroRNAs: Novel Players in Cancer Diagnosis and Therapies Oom, Aaron L. Humphries, Brock A. Yang, Chengfeng Biomed Res Int Review Article First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research. Hindawi Publishing Corporation 2014 2014-07-02 /pmc/articles/PMC4101974/ /pubmed/25101302 http://dx.doi.org/10.1155/2014/959461 Text en Copyright © 2014 Aaron L. Oom et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Oom, Aaron L.
Humphries, Brock A.
Yang, Chengfeng
MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title_full MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title_fullStr MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title_full_unstemmed MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title_short MicroRNAs: Novel Players in Cancer Diagnosis and Therapies
title_sort micrornas: novel players in cancer diagnosis and therapies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101974/
https://www.ncbi.nlm.nih.gov/pubmed/25101302
http://dx.doi.org/10.1155/2014/959461
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