Cargando…

Involvement of Different CD4(+) T Cell Subsets Producing Granzyme B in the Immune Response to Leishmania major Antigens

The nature of effector cells and the potential immunogenicity of Leishmania major excreted/secreted proteins (LmES) were evaluated using peripheral blood mononuclear cells (PBMCs) from healed zoonotic cutaneous leishmaniasis individuals (HZCL) and healthy controls (HC). First, we found that PBMCs fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naouar, Ikbel, Boussoffara, Thouraya, Ben Ahmed, Melika, Belhaj Hmida, Nabil, Gharbi, Adel, Gritli, Sami, Ben Salah, Afif, Louzir, Hechmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102068/ https://www.ncbi.nlm.nih.gov/pubmed/25104882 http://dx.doi.org/10.1155/2014/636039

Ejemplares similares

Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production
por: Naouar, Ikbel, et al.
Publicado: (2016)

Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection
por: Boussoffara, Thouraya, et al.
Publicado: (2018)

Human Cellular Immune Response to the Saliva of Phlebotomus papatasi Is Mediated by IL-10-Producing CD8+ T Cells and Th1-Polarized CD4+ Lymphocytes
por: Abdeladhim, Maha, et al.
Publicado: (2011)

Histological and immunological differences between zoonotic cutaneous leishmaniasis due to Leishmania major and sporadic cutaneous leishmaniasis due to Leishmania infantum
por: Boussoffara, Thouraya, et al.
Publicado: (2019)

Activated cytotoxic T cells within zoonotic cutaneous leishmaniasis lesions
por: Boussoffara, Thouraya, et al.
Publicado: (2019)

Human cellular and humoral immune responses to Phlebotomus papatasi salivary gland antigens in endemic areas differing in prevalence of Leishmania major infection
por: Kammoun-Rebai, Wafa, et al.
Publicado: (2017)

A prospective cohort study of Cutaneous Leishmaniasis due to Leishmania major: Dynamics of the Leishmanin skin test and its predictive value for protection against infection and disease
por: Bettaieb, Jihène, et al.
Publicado: (2020)

Validation of Recombinant Salivary Protein PpSP32 as a Suitable Marker of Human Exposure to Phlebotomus papatasi, the Vector of Leishmania major in Tunisia
por: Marzouki, Soumaya, et al.
Publicado: (2015)

Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis
por: Kammoun-Rebai, Wafa, et al.
Publicado: (2016)

Immunological Aspects of Systemic Vasculitis
por: Ben Ahmed, Melika, et al.
Publicado: (2011)

Psycho-social impacts, experiences and perspectives of patients with Cutaneous Leishmaniasis regarding treatment options and case management: An exploratory qualitative study in Tunisia
por: Boukthir, Aicha, et al.
Publicado: (2020)

Intra-Specific Diversity of Leishmania major Isolates: A Key Determinant of Tunisian Zoonotic Cutaneous Leishmaniasis Clinical Polymorphism
por: Attia, Hanene, et al.
Publicado: (2022)

Healed Lesions of Human Cutaneous Leishmaniasis Caused By Leishmania major Do Not Shelter Persistent Residual Parasites
por: Sghaier, Rabiaa M., et al.
Publicado: (2022)

Prevalence and determinants of Leishmania major infection in emerging and old foci in Tunisia
por: Bettaieb, Jihene, et al.
Publicado: (2014)

Imaging Leishmania major Antigens in Experimentally Infected Macrophages and Dermal Scrapings from Cutaneous Leishmaniasis Lesions in Tunisia
por: Saïdi, Nasreddine, et al.
Publicado: (2022)

First report of naturally infected Sergentomyia minuta with Leishmania major in Tunisia
por: Jaouadi, Kaouther, et al.
Publicado: (2015)

Immunogenicity of Mix-and-Match CoronaVac/BNT162b2 Regimen versus Homologous CoronaVac/CoronaVac Vaccination: A Single-Blinded, Randomized, Parallel Group Superiority Trial
por: Samoud, Samar, et al.
Publicado: (2023)

Salivary Antigen SP32 Is the Immunodominant Target of the Antibody Response to Phlebotomus papatasi Bites in Humans
por: Marzouki, Soumaya, et al.
Publicado: (2012)

The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
por: Chollat-Namy, Marie, et al.
Publicado: (2019)

Expression of endogenous granzyme B in a subset of human primary breast carcinomas
por: Hu, S X, et al.
Publicado: (2003)

Implementationthe“5S-Kaizen-TQM”approach into public Hospital in Tunisia
por: Hammami, Sondes, et al.
Publicado: (2022)

Implicating bites from a leishmaniasis sand fly vector in the loss of tolerance in pemphigus
por: Marzouki, Soumaya, et al.
Publicado: (2020)

Knowledge, attitudes and uptake related to influenza vaccine among healthcare workers during the 2018–2019 influenza season in Tunisia
por: Cherif, Ines, et al.
Publicado: (2021)

Influenza vaccination knowledge, attitudes, and practices among Tunisian elderly with chronic diseases
por: Kharroubi, Ghassen, et al.
Publicado: (2021)

Updating the Salivary Gland Transcriptome of Phlebotomus papatasi (Tunisian Strain): The Search for Sand Fly-Secreted Immunogenic Proteins for Humans
por: Abdeladhim, Maha, et al.
Publicado: (2012)

RAPD-PCR reveals genetic polymorphism among Leishmania major strains from Tunisian patients
por: Yazidi, Rihab, et al.
Publicado: (2015)

Genotype Profile of Leishmania major Strains Isolated from Tunisian Rodent Reservoir Hosts Revealed by Multilocus Microsatellite Typing
por: Ghawar, Wissem, et al.
Publicado: (2014)

Infection of Human Neutrophils With Leishmania infantum or Leishmania major Strains Triggers Activation and Differential Cytokines Release
por: Oualha, Rafeh, et al.
Publicado: (2019)

Macroscopic anatomy, radiography and computed tomography of normal paranasal sinuses of the adult one‐humped dromedary (Camelus dromedarius)
por: Ben Khalifa, Abdelmoneme, et al.
Publicado: (2021)

Ecological niche modeling predicting the potential distribution of Leishmania vectors in the Mediterranean basin: impact of climate change
por: Chalghaf, Bilel, et al.
Publicado: (2018)

First Report of Two Jaculus Rodents as Potential Reservoir Hosts of Leishmania Parasites in Tunisia
por: Ghawar, Wissem, et al.
Publicado: (2022)

Incidence and risk factors of SARS-CoV-2 infection among workers in a public health laboratory in Tunisia
por: Kharroubi, Ghassen, et al.
Publicado: (2023)

Case Report: Allergic Bronchopulmonary Aspergillosis Revealing Asthma
por: Snen, Houda, et al.
Publicado: (2021)

WR279,396, a Third Generation Aminoglycoside Ointment for the Treatment of Leishmania major Cutaneous Leishmaniasis: A Phase 2, Randomized, Double Blind, Placebo Controlled Study
por: Ben Salah, Afif, et al.
Publicado: (2009)

Spatio-temporal Genetic Structuring of Leishmania major in Tunisia by Microsatellite Analysis
por: Harrabi, Myriam, et al.
Publicado: (2015)

The Role of Dietary Intake in Type 2 Diabetes Mellitus: Importance of Macro and Micronutrients in Glucose Homeostasis
por: Kheriji, Nadia, et al.
Publicado: (2022)

Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis
por: García‐Laorden, M. Isabel, et al.
Publicado: (2021)

Impairment of Granzyme B-Producing Regulatory B Cells Correlates with Exacerbated Rheumatoid Arthritis
por: Xu, Liling, et al.
Publicado: (2017)

Granzyme A–producing T helper cells are critical for acute graft-versus-host disease
por: Park, Sungtae, et al.
Publicado: (2020)

Knowledge attitudes and practices toward seasonal influenza vaccine among pregnant women during the 2018/2019 influenza season in Tunisia
por: Dhaouadi, Sonia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eqvabo84ftbofvhmultj45qkdu